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Description

APT1 is a depalmitoylase for ATG2A To determine the depalmitoylase responsible for ATG2A, we initiated our investigation by examining the interacting proteins of ATG2A

What NAPQI does: Directly binds to and damages cellular proteins Depletes glutathione rapidly Generates oxidative stress which damages DNA Triggers cell death Damages mitochondria, disrupting energy production NAPQI crosses the placenta and depletes fetal brain glutathione at doses below those causing maternal liver toxicity